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Step 4: Applying the Evidence

Once you have determined that a study is internally valid (step 3), you must decide how the study and/or other information applies to your question. To reach your conclusion you may consult questions related to diagnosis, therapy, harm, and prognosis. Keep in mind that you must interpret the information based on a number of criteria and depending on your skill and experience, you may need to confer with a peer.

Click each icon to see questions you may ask to help determine how evidence applies.

Click the References button for additional information about applying evidence.